Intense Pulsed Light (IPL) therapy improves various clinical symptoms of photoaging skin. In this study we have investigated clinical eVects of a novel IPL, Lumenis One™ (LUMENIS, Tokyo) on facial pigmentary lesions in 18 Japanese female patients. Measurement was performed after 3–5 treatments. IPL showed marked and slight improvements in 28 and 39%, respectively. The data of melanin index demonstrated the improvement after IPL therapy. These results indicated that IPL therapy using Lumenis One may be useful to treat solar lentigines and ephelides on the face.